The Thyroid and Vitamin B1
What is Vitamin B1?
Definition: Vitamin B1, also known as thiamine, is a water-soluble vitamin essential for energy metabolism and the proper functioning of the nervous system. It is one of the B-complex vitamins.
Origin: The body cannot produce thiamine, so it must be obtained from dietary sources or supplements.
What types of Vitamin B1 are there and what do they do?
Natural Forms: Thiamine exists in food primarily as thiamine pyrophosphate (TPP), the active form of the vitamin.
Synthetic Forms:
Thiamine hydrochloride and thiamine mononitrate are used in supplements and fortified foods.
Benfotiamine: A fat-soluble derivative often used for diabetic complications.
Functions: All forms play a role in carbohydrate metabolism, energy production, and nervous system health.
Daily Requirements for Vitamin B1 in all demographics
Infants (0-6 months): 0.2 mg/day
Children (1-3 years): 0.5 mg/day
Adolescents (9-13 years): 0.9 mg/day
Adults (18+ years): 1.1 mg/day for women, 1.2 mg/day for men
Pregnancy and Lactation: 1.4 mg/day to support increased metabolic needs.
What does Vitamin B1 do in our body?
Energy Production: Acts as a coenzyme in the breakdown of glucose for ATP production.
Nerve Function: Essential for the synthesis of neurotransmitters, promoting nerve signal transmission.
Muscle Contraction: Supports proper muscular function by aiding in nerve-muscle coordination.
Symptoms of Vitamin B1 Deficiency
Mild Deficiency: Fatigue, irritability, poor memory, and muscle weakness.
Severe Deficiency:
Beriberi is characterized by muscle wasting, weakness, and cardiovascular issues.
Wernicke-Korsakoff Syndrome: A neurological disorder caused by chronic deficiency, common in alcoholics.
What does Vitamin B1 do for our thyroid pathway?
Energy for Thyroid Function: Enhances energy metabolism, which is crucial for thyroid hormone production and utilization.
Oxidative Stress Reduction: Protects thyroid cells from oxidative damage.
Immune Support: Strengthens the immune system, reducing autoimmune attacks on the thyroid.
What does Vitamin B1 do for our Liver?
Detoxification: Assists the liver in metabolizing toxins through enzymatic processes.
Energy Supply: Supports carbohydrate metabolism in liver cells, maintaining optimal liver function.
Fat Metabolism: Helps prevent fatty liver by aiding in the proper breakdown of fats.
What does Vitamin B1 do for our gut?
Digestion Support: Enhances carbohydrate digestion and absorption.
Gut-Brain Axis: Promotes healthy gut microbiota, indirectly supporting mental health.
Motility Regulation: Improves gut motility, reducing the risk of constipation.
Physical Ailments that affect Vitamin B1
Alcoholism: Interferes with absorption and storage of thiamine.
Diabetes: Increased excretion of thiamine in urine, leading to deficiency.
Celiac Disease: Impairs absorption of thiamine due to intestinal damage.
Food that impacts Vitamin B1
Thiaminases: Found in raw fish and shellfish, these enzymes break down thiamine.
Anti-nutrients: Polyphenols in tea and coffee can reduce absorption.
Medications that Impact Vitamin B1
Diuretics: Increase urinary excretion of thiamine.
Antibiotics: Prolonged use can disrupt gut flora, reducing thiamine synthesis.
Chemotherapy Drugs: Can interfere with thiamine metabolism.
Natural Supplements that negatively impact Vitamin B1
High-dose Vitamin C: May degrade thiamine in large quantities.
Calcium Supplements: Excess calcium can impair thiamine absorption.
Heavy Metals that Impact Vitamin B1
Lead and Mercury: Deplete thiamine stores and disrupt enzyme activity.
Cadmium: Interferes with thiamine-dependent enzymatic reactions.
Testing for Vitamin B1
Blood Tests: Measure thiamine levels directly in the blood.
Erythrocyte Transketolase Activity: Assesses enzyme activity dependent on thiamine.
Nutrients Required for Vitamin B1 Absorption
Magnesium: Aids in the activation of thiamine to its coenzyme form.
Zinc: Supports thiamine-dependent enzymatic reactions.
Foods high in Vitamin B1
Whole Grains: Brown rice, oats, and wheat germ.
Meats: Pork, liver, and chicken.
Legumes: Lentils, black beans, and peas.
Seeds and Nuts: Sunflower seeds and flaxseeds.
A Recipe high in Vitamin B1
Thiamine Boosting Stir-Fry: Combine pork strips, brown rice, and a mix of green vegetables like broccoli and spinach. Use sesame seeds as a topping for extra nutrients.
Other Random Information about Vitamin B1
Heat Sensitivity: Thiamine is destroyed by prolonged cooking or high heat.
Storage in the Body: Thiamine has a short half-life, so consistent dietary intake is essential.
Mental Health: Adequate thiamine levels are linked to reduced anxiety and better cognitive performance.
Disclaimer: The information provided in this article is for educational purposes only and is not intended to diagnose, treat, or cure any medical condition. Always consult with a qualified healthcare professional before making any changes to your diet, lifestyle, or treatment plan. Individual needs may vary, and what works for one person may not be suitable for another.