The Thyroid and Vitamin B1

What is Vitamin B1?

  • Definition: Vitamin B1, also known as thiamine, is a water-soluble vitamin essential for energy metabolism and the proper functioning of the nervous system. It is one of the B-complex vitamins.

  • Origin: The body cannot produce thiamine, so it must be obtained from dietary sources or supplements.

What types of Vitamin B1 are there and what do they do?

  • Natural Forms: Thiamine exists in food primarily as thiamine pyrophosphate (TPP), the active form of the vitamin.

  • Synthetic Forms:

    • Thiamine hydrochloride and thiamine mononitrate are used in supplements and fortified foods.

    • Benfotiamine: A fat-soluble derivative often used for diabetic complications.

  • Functions: All forms play a role in carbohydrate metabolism, energy production, and nervous system health.

Daily Requirements for Vitamin B1 in all demographics

  • Infants (0-6 months): 0.2 mg/day

  • Children (1-3 years): 0.5 mg/day

  • Adolescents (9-13 years): 0.9 mg/day

  • Adults (18+ years): 1.1 mg/day for women, 1.2 mg/day for men

  • Pregnancy and Lactation: 1.4 mg/day to support increased metabolic needs.

What does Vitamin B1 do in our body?

  • Energy Production: Acts as a coenzyme in the breakdown of glucose for ATP production.

  • Nerve Function: Essential for the synthesis of neurotransmitters, promoting nerve signal transmission.

  • Muscle Contraction: Supports proper muscular function by aiding in nerve-muscle coordination.

Symptoms of Vitamin B1 Deficiency

  • Mild Deficiency: Fatigue, irritability, poor memory, and muscle weakness.

  • Severe Deficiency:

    • Beriberi is characterized by muscle wasting, weakness, and cardiovascular issues.

    • Wernicke-Korsakoff Syndrome: A neurological disorder caused by chronic deficiency, common in alcoholics.

What does Vitamin B1 do for our thyroid pathway?

  • Energy for Thyroid Function: Enhances energy metabolism, which is crucial for thyroid hormone production and utilization.

  • Oxidative Stress Reduction: Protects thyroid cells from oxidative damage.

  • Immune Support: Strengthens the immune system, reducing autoimmune attacks on the thyroid.

What does Vitamin B1 do for our Liver?

  • Detoxification: Assists the liver in metabolizing toxins through enzymatic processes.

  • Energy Supply: Supports carbohydrate metabolism in liver cells, maintaining optimal liver function.

  • Fat Metabolism: Helps prevent fatty liver by aiding in the proper breakdown of fats.

What does Vitamin B1 do for our gut?

  • Digestion Support: Enhances carbohydrate digestion and absorption.

  • Gut-Brain Axis: Promotes healthy gut microbiota, indirectly supporting mental health.

  • Motility Regulation: Improves gut motility, reducing the risk of constipation.

Physical Ailments that affect Vitamin B1

  • Alcoholism: Interferes with absorption and storage of thiamine.

  • Diabetes: Increased excretion of thiamine in urine, leading to deficiency.

  • Celiac Disease: Impairs absorption of thiamine due to intestinal damage.

Food that impacts Vitamin B1

  • Thiaminases: Found in raw fish and shellfish, these enzymes break down thiamine.

  • Anti-nutrients: Polyphenols in tea and coffee can reduce absorption.

Medications that Impact Vitamin B1

  • Diuretics: Increase urinary excretion of thiamine.

  • Antibiotics: Prolonged use can disrupt gut flora, reducing thiamine synthesis.

  • Chemotherapy Drugs: Can interfere with thiamine metabolism.

Natural Supplements that negatively impact Vitamin B1

  • High-dose Vitamin C: May degrade thiamine in large quantities.

  • Calcium Supplements: Excess calcium can impair thiamine absorption.

Heavy Metals that Impact Vitamin B1

  • Lead and Mercury: Deplete thiamine stores and disrupt enzyme activity.

  • Cadmium: Interferes with thiamine-dependent enzymatic reactions.

Testing for Vitamin B1

  • Blood Tests: Measure thiamine levels directly in the blood.

  • Erythrocyte Transketolase Activity: Assesses enzyme activity dependent on thiamine.

Nutrients Required for Vitamin B1 Absorption

  • Magnesium: Aids in the activation of thiamine to its coenzyme form.

  • Zinc: Supports thiamine-dependent enzymatic reactions.

Foods high in Vitamin B1

  • Whole Grains: Brown rice, oats, and wheat germ.

  • Meats: Pork, liver, and chicken.

  • Legumes: Lentils, black beans, and peas.

  • Seeds and Nuts: Sunflower seeds and flaxseeds.

A Recipe high in Vitamin B1

  • Thiamine Boosting Stir-Fry: Combine pork strips, brown rice, and a mix of green vegetables like broccoli and spinach. Use sesame seeds as a topping for extra nutrients.

Other Random Information about Vitamin B1

  • Heat Sensitivity: Thiamine is destroyed by prolonged cooking or high heat.

  • Storage in the Body: Thiamine has a short half-life, so consistent dietary intake is essential.

  • Mental Health: Adequate thiamine levels are linked to reduced anxiety and better cognitive performance.

Disclaimer: The information provided in this article is for educational purposes only and is not intended to diagnose, treat, or cure any medical condition. Always consult with a qualified healthcare professional before making any changes to your diet, lifestyle, or treatment plan. Individual needs may vary, and what works for one person may not be suitable for another.

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The Thyroid and Vitamin B2

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