The Thyroid and Iodine

What is Iodine?

  • Definition: Iodine is a trace mineral essential for the production of thyroid hormones, which regulate metabolism, growth, and development in the body.

  • Sources: Found in seafood, iodized salt, dairy, and some plants grown in iodine-rich soil. It’s also available as a supplement.

What Types of Iodine Are There and What Do They Do?

  • Potassium Iodide and Sodium Iodide: Commonly used in supplements and medications to prevent and treat iodine deficiency.

  • Elemental Iodine: Used in disinfectants and sometimes in medical imaging.

  • Iodate: Added to salt in some countries as a fortification method.

  • Lugol’s Iodine Solution: A mix of iodine and potassium iodide, often used topically or in small doses for supplementation.

  • Radioactive Iodine: Used in medical imaging and treatments for thyroid conditions such as hyperthyroidism or thyroid cancer.

Daily Requirements for Iodine

  • Infants (0-12 months): 110-130 µg/day.

  • Children (1-8 years): 90 µg/day.

  • Children (9-13 years): 120 µg/day.

  • Adolescents and Adults (14+ years): 150 µg/day.

  • Pregnant Women: 220 µg/day.

  • Lactating Women: 290 µg/day.

  • Upper Tolerable Intake Level: 1,100 µg/day for adults.

What Does Iodine Do in Our Body?

  • Thyroid Hormone Production: Crucial for the synthesis of thyroxine (T4) and triiodothyronine (T3), hormones that regulate metabolic processes.

  • Cognitive Function: Essential during pregnancy and infancy for brain development and cognitive function.

  • Immune Support: Plays a role in maintaining a healthy immune system by supporting cellular defense mechanisms.

Symptoms of Iodine Deficiency

  • Goiter: Enlargement of the thyroid gland.

  • Hypothyroidism: Fatigue, weight gain, cold intolerance, depression.

  • Cognitive Impairment: Poor focus, developmental delays in children.

  • Hair Loss and Skin Issues: Dry skin, hair thinning, or hair loss.

  • Cretinism: Severe iodine deficiency in pregnancy can result in stunted growth and intellectual disabilities in infants.

What Does Iodine Do for Our Thyroid Pathway?

  • Hormone Synthesis: Iodine combines with tyrosine in the thyroid gland to form T3 and T4.

  • Regulation: Helps control metabolic rate, energy levels, and overall cellular function.

  • Thyroid Function: Adequate iodine levels prevent thyroid dysfunction, including hypothyroidism and hyperthyroidism.

What Does Iodine Do for Our Liver?

  • Detoxification: Supports liver detox pathways by assisting in hormone metabolism and reducing oxidative stress.

  • Hormone Balance: Helps maintain optimal conversion of T4 to the more active T3 hormone in the liver.

What Does Iodine Do for Our Gut?

  • Microbial Balance: Plays a role in maintaining gut flora and preventing overgrowth of harmful bacteria.

  • Digestive Health: Indirectly supports gut motility and nutrient absorption by regulating metabolic processes.

Physical Ailments That Affect Iodine

  • Autoimmune Conditions: Hashimoto’s thyroiditis and Graves’ disease can affect iodine utilization.

  • Iodine Deficiency Disorders: Include goiter, hypothyroidism, and developmental issues in children.

  • Thyroid Nodules: Imbalance in iodine levels can lead to nodule formation.

Foods That Impact Iodine

  • Goitrogens: Found in cruciferous vegetables (broccoli, kale, cauliflower) and soy products; they can interfere with iodine absorption when consumed in large quantities.

  • Excess Salt: High sodium intake without iodization can dilute iodine’s effectiveness.

Medications That Impact Iodine

  • Amiodarone: Contains high iodine levels and can cause thyroid dysfunction.

  • Lithium: Can inhibit iodine uptake by the thyroid.

  • Anti-Thyroid Drugs: Medications like methimazole and propylthiouracil interfere with iodine utilization.

Natural Supplements That Negatively Impact Iodine

  • Excessive Seaweed Supplements: High iodine content can disrupt thyroid balance.

  • Calcium and Iron: Taken in high doses, these can interfere with iodine absorption.

Heavy Metals That Impact Iodine

  • Fluoride: Competes with iodine in the thyroid gland.

  • Bromine: Found in some baked goods and soft drinks, it can block iodine uptake.

  • Mercury: Can disrupt thyroid function and reduce iodine effectiveness.

Testing for Iodine

  • Urinary Iodine Test: Measures iodine levels to assess deficiency.

  • Thyroid Function Tests: Includes TSH, T3, and T4 levels to evaluate iodine’s effect on thyroid health.

  • Iodine Patch Test: A less reliable method where iodine is applied to the skin.

Nutrients Required for Iodine Absorption

  • Selenium: Essential for converting T4 to T3 and protecting the thyroid gland.

  • Zinc: Supports thyroid hormone production.

  • Iron: Necessary for thyroid hormone synthesis.

  • Vitamin A: Helps regulate iodine’s role in thyroid function.

Foods High in Iodine

  • Seaweed: Kelp, nori, and wakame are the richest sources.

  • Fish and Shellfish: Cod, shrimp, and tuna.

  • Dairy Products: Milk, yogurt, and cheese.

  • Eggs: Particularly the yolk.

  • Iodized Salt: A simple way to boost iodine intake.


A Recipe High in Iodine

Seaweed Salad with Sesame Dressing

Ingredients: 1 cup dried wakame or choice of seaweed, 2 tbsp soy sauce or tamari, 1 tbsp rice vinegar, 1 tbsp sesame oil, 1 tsp grated ginger, 1 tbsp sesame seeds

Instructions: Soak seaweed in water for 10 mins then drain, mix other ingredients then toss the seaweed in it. Sprinkle with sesame seeds.


Other Random Information About Iodine

  • Iodine Fortification: Introduced to combat widespread deficiency; it’s particularly effective in countries with iodized salt programs.

  • Over-supplementation Risks: Too much iodine can cause thyroid dysfunction, including hyperthyroidism or thyroiditis.

  • Pregnancy Importance: Ensuring adequate iodine levels during pregnancy prevents birth defects and developmental delays.

  • Geographic Variations: Coastal regions tend to have higher iodine levels due to seafood consumption, while inland areas may be more prone to deficiency.

Disclaimer: The information provided in this article is for educational purposes only and is not intended to diagnose, treat, or cure any medical condition. Always consult with a qualified healthcare professional before making any changes to your diet, lifestyle, or treatment plan. Individual needs may vary, and what works for one person may not be suitable for another.

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The Thyroid and Folate

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The Thyroid and Boron